New Brunswick

Only 323 people prescribed COVID-19 medication Paxlovid so far

New Brunswick has now received 3,550 treatment courses of Paxlovid, the antiviral drug treatment for COVID-19.

Province has received 3,550 treatment courses, no word on expanding eligibility as case counts rise

For each dose of Paxlovid, patients take two tablets of nirmatrelvir and one tablet of ritonavir. The combination of antivirals help stop the coronavirus from multiplying and infecting more cells. (Cory Herperger/Radio-Canada)

New Brunswick has now received 3,550 treatment courses of Paxlovid, the antiviral drug treatment for COVID-19.

That's up from its first shipment of 700 from the federal government in January, after the pills made by Pfizer were approved by Health Canada.

But only 323 people have received the drug so far, according to Department of Health spokesperson Bruce Macfarlane.

He did not immediately respond to questions about why only nine per cent of the supply has been dispensed.

Although Paxlovid has been hailed by some doctors as a pandemic "game changer" that could relieve some of the pressure on the health-care system, people across the country have told CBC News they've faced obstacles accessing the treatment.

To be effective, Paxlovid must be taken within five days of developing symptoms and it's limited to adults with mild to moderate COVID-19 who are at high risk of progressing to serious disease, including hospitalization or death.

Macfarlane did not immediately respond to questions about how New Brunswick is faring at meeting the demand as case counts climb now that all provincial COVID-19 restrictions, such as isolation, masking and physical distancing, have been lifted.

Paxlovid is designed to help the body fight off the SARS-CoV-2 virus, reduce symptoms from an infection and shorten the period of illness.

Those who are currently eligible to receive a prescription for Paxlovid from a primary care practitioner in New Brunswick include:

  • People 80 and older
  • People 18 and older who are immunocompromised by active or recent cancer treatment within the past months, a solid organ transplant, a stem cell transplant within the past years, moderate to severe primary immunodeficiency or advanced or untreated HIV infection, or moderate to severe immunosuppressive treatment, such as biologic medications or high-dose systemic corticosteroids
  • People 60-79 years of age who are partially or "under vaccinated," meaning they don't have all the vaccine doses they are eligible for
  • People 60-79 years of age who either live in a long-term care home or receive home care, or are from or live in a First Nations community

Not everyone who is eligible is able to take Paxlovid because the drug interacts with other medications.

Macfarlane did not immediately provide any breakdown of the 323 people who have received the drug to date or provide any information about the treatment's success.

Asked whether the province is considering expanding eligibility to other groups, such as those with underlying conditions, such as diabetes or obesity, he did not immediately respond.

Nor did he immediately say whether the province is considering following the lead of Quebec and give pharmacists the authority to prescribe Paxlovid to improve access. Quebec is the only jurisdiction in Canada to have done so. In addition, all 1,900 community pharmacies will also carry the medication.

Macfarlane did say Paxlovid is currently being distributed by 55 community pharmacies across New Brunswick.

He did not immediately say when the province is scheduled to receive more Paxlovid or how much more is expected.

As of March 31, Health Canada said it has shipped enough doses for 150,000 people to the provinces and territories, allocated on a per capita basis. 

Hospitalizations reach record high

New Brunswick reported nine more COVID-related deaths and 78 people in hospital because of the virus in its new weekly report called COVIDWATCH Tuesday.

People who are initially admitted to hospital for another reason and later test positive for COVID are no longer included.

But Chief Medical Officer of Health Dr. Jennifer Russell told CBC the combined total is actually 178 — an increase of 36 from the previous week and a new record high. The previous record was 165 on Feb. 2.

Nine people require intensive care.

There are 8,670 new cases of COVID, including 3,888 PCR-confirmed tests and 4,782 self-reported rapid tests. The province's active case count now stands at 6,134, an increase of 1,181.

Paxlovid combines a new antiviral drug developed by Pfizer called nirmatrelvir with an existing antiretroviral drug named ritonavir.

Nirmatrelvir interferes with the proteins the coronavirus needs to multiply and stops it from infecting more cells. Ritonavir slows the breakdown of nirmatrelvir so it stays in the body long enough to do its job. 

A full course of treatment requires a patient to take 30 pills — two nirmatrelvir and one ritonavir taken together twice a day for five days.

In November, Pfizer reported that Paxlovid reduced the risk of hospitalization or death by 89 per cent compared to a placebo in non-hospitalized high-risk adults with COVID-19.