Cardinals remain unbeaten with dominant victory over injury-riddled Browns

Kyler Murray threw four touchdown passes as the Arizona Cardinals remained the NFL's only unbeaten team and continued their best start since 1974 — without coach Kliff Kingsbury on Sunday — with a 37-14 win over the battered, reeling Cleveland Browns.

The Cardinals (6-0) built a 20-0 lead in the first half and kept their perfect record intact despite not having Kingsbury or star linebacker Chandler Jones, who both tested positive for COVID-19 this week.

Murray connected with DeAndre Hopkins for two TDs, and Arizona's shifty quarterback came up with a clutch play whenever the Cardinals needed one.

The Browns (3-3) have lost two straight under coach Kevin Stefanski for the first time and Cleveland has bigger concerns, most notably to a growing list of major injuries. The latest was to running back Kareem Hunt, carted to the locker room in the fourth quarter with a calf injury.

Cleveland was already missing star running back Nick Chubb (calf) and the Browns, who host Denver on Thursday night, played without both their starting offensive tackles.

Packers down division rival Bears for 5th straight win

Aaron Rodgers threw for two touchdowns and ran for another as the Packers (5-1) beat the Bears (3-3) for the 20th time in 23 games counting the playoffs and improved to 22-5 with Rodgers as the starter against Chicago.

Rodgers shook off a sluggish start, throwing a 1-yard touchdown to Allen Lazard in the second quarter and a 12-yarder to Aaron Jones in the third, making it 17-7.

Rodgers put away the Bears after Justin Fields threw a 5-yard touchdown to Darnell Mooney, cutting the lead to three with 8:44 left. He scored from the 6 to cap a 75-yard drive, bumping the lead back up to 10. He then turned toward the crowd and yelled, "I still own you! I still own you!"

Davante Adams caught four passes for 89 yards. Aaron Jones ran for 76 yards and caught four passes for 34, helping the Packers remain unbeaten since a season-opening 38-3 loss to New Orleans in Jacksonville.

Jaguars snap 2nd-longest losing streak in Super Bowl era

The Jacksonville Jaguars ended their 20-game losing streak when Matthew Wright kicked a 53-yard field goal as time expired in a 23-20 victory over the Miami Dolphins on Sunday in London.

Trevor Lawrence connected on a short slant pass to Laviska Shenault Jr. and the Jags (1-5) called timeout with 1 second remaining after the Dolphins (1-5) gambled on a fourth-and-1 from their 46 and came up short.

Lawrence threw for 319 yards and a touchdown as he and coach Urban Meyer finally earned their first NFL victories — even if it required a trip to Europe to get it done in a "home" game at Tottenham Hotspur Stadium.

The Dolphins lost their fifth consecutive game, spoiling the return of Tua Tagovailoa, who made his first start in a month. The second-year quarterback threw two touchdown passes to Jaylen Waddle.

Before Sunday, the Jags hadn't won a game since beating Indianapolis 27-20 in the 2020 season opener. The 20-game losing streak is the second longest in the Super Bowl era.

Raiders win in 1st game since Gruden resignation

Derek Carr sliced up the Denver defence for 341 yards and two touchdowns, Maxx Crosby made three sacks and the Las Vegas Raiders started the post-Jon Gruden era with a 34-24 thrashing of the bewildered Broncos on Sunday.

The Raiders (4-2) gave longtime special teams coordinator Rich Bisaccia a win in his debut as interim head coach and offensive coordinator Greg Olson was masterful in his first play-calling duties for Las Vegas since Carr's rookie season in 2014.

The Raiders began by ending an 11-game streak without a score on their opening drive. They never let up, burning the Broncos' beleaguered secondary that couldn't keep up with Carr and his targets.

Nor could Denver's deficient offence keep pace. Teddy Bridgewater threw a season-high three interceptions and lost a fumble, negating his 334 yards passing and three TDs.

Prescott TD pass lifts Cowboys over Pats in OT

Dak Prescott threw 35-yard touchdown pass to CeeDee Lamb in overtime, and the Dallas Cowboys survived a wild finish to beat New England 35-29 on Sunday, their first win over Bill Belichick's Patriots.

Dallas hadn't won at New England since 1987 and was 0-5 against Belichick. The Cowboys (5-1) have won five straight, their longest winning streak since 2016.

The Cowboys led 17-14 entering the fourth quarter, and that's when the fun began. The teams traded five scores in the period, three in the final 2 1/2 minutes.

New England (2-4) was clinging to a 21-20 lead when sensational Cowboys cornerback Trevon Diggs intercepted Mac Jones and returned it 42 yards for a touchdown — his seventh pick and second pick-6 of the season — to put Dallas ahead 26-20. On the next play from scrimmage, Jones hit Kendrick Bourne for a 75-yard score. Jones hooked up with Jakobi Meyers for the 2-point conversion.

But Prescott led the Cowboys on a 40-yard drive and Greg Zuerlein's 49-yard field goal sent it to overtime. Dallas ended it after New England punted on its first possession as the Patriots dropped to 0-4 at home for the first time in Belichick's 22 years as coach.

Ravens frustrate Justin Herbert, Chargers

Lamar Jackson threw for 167 yards and a touchdown, and the Baltimore Ravens frustrated Justin Herbert and the Los Angeles Chargers in a 34-6 victory Sunday.

A week after scoring 47 points in a win over Cleveland, the Chargers (4-2) came up empty on their first five possessions and were held under 16 points for only the second time since drafting Herbert before last season.

The Ravens completely controlled this matchup of division leaders. Each of Baltimore's three veteran running backs — Latavius Murray, Le'Veon Bell and Devonta Freeman — scored a touchdown.

Jackson went 19 of 27 with two interceptions. Herbert was 22 of 39 for 195 yards with a touchdown and an interception. Although the much-anticipated clash between these two talented quarterbacks didn't live up to expectations, Baltimore (5-1) won with a total team effort.

Stafford throws 4 TDs in Rams' victory

Matthew Stafford threw three of his four touchdown passes in a 28-point second quarter. Stafford connected with prime target Cooper Kupp on scoring passes of 3 and 13 yards. He also found Robert Woods for a 15-yard score and running back Darrell Henderson on a 25-yarder.

Stafford, who has 16 TD passes in six games, finished 22 of 28 for 251 yards in three-plus quarters. The Rams (5-1) took advantage of two short fields provided by their defence for easy TDs in breaking the game open early against New York (1-5).

Kupp, who was tied for second in the league with 37 catches entering the game, added nine more receptions for 130 yards. Safety Taylor Rapp had two interceptions to account for half of Los Angeles' four takeaways.

A week after sustaining a concussion in a loss to Dallas, Daniel Jones started at quarterback for the Giants. He led the offence to a 27-yard field goal by Graham Gano on the opening series, but the Rams picked him off three times and recovered a fumble on a strip-sack by Ogbonnia Okoronkwo.

Kansas City defeats Washington

Patrick Mahomes threw for 397 yards and engineered three second-half touchdown drives to compensate for a pair of interceptions.

After throwing two picks before halftime, Mahomes connected with Tyreek Hill on a 2-yard touchdown pass late in the third quarter. He put the game out of reach with a 24-yarder to Demarcus Robinson with 3:14 left in the fourth period. In between, new starting running back Darrel Williams rushed for his second TD of the game to help Kansas City (3-3) avoid what would have been an embarrassing loss.

The defence also finally played its part, holding an opponent under 29 points for the first time this season, forcing a fumble and picking off Taylor Heinicke to seal the win. Washington (2-4) finished with 276 yards and its lowest points total of the season.

Unlike losses to the Ravens, Chargers and Bills, the KC offence made up for the giveaways. Kansas City had touchdown drives of 95, 68, 45 and 96 yards.

Mahomes finished 32 of 47, and rushed for 31 yards along the way.

Colts bounce back to down Texans

Carson Wentz threw two touchdown passes, Jonathan Taylor ran for two more and the Indianapolis defence held up.

Indy rebounded from an embarrassing fourth-quarter collapse at Baltimore by winning for the second time in three weeks. The Colts (2-4) can now move within one game of the AFC South lead — if Buffalo beats Tennessee on Monday.

Houston (1-5) has lost five straight overall and six of the last seven against the Colts.

And this one changed quickly in the second half — in the exact opposite direction of the Monday night fiasco.

Two-time All-Pro linebacker Darius Leonard picked off rookie quarterback Davis Mills on Houston's first play of the third quarter. Wentz capitalized two plays later with a 28-yard TD pass to Mo Alie-Cox to make it 17-3.

Taylor started Indy's next series with an 83-yard run and capped it with a 4-yard TD rush to make it 24-3, and the reeling Texans spent the rest of the game futilely playing catch-up and getting nowhere.

Bengals rout Lions

Joe Burrow tied a career high with three touchdown passes, helping the Bengals (4-2) equal last year's number of wins and double their victories from 2019 during coach Zac Taylor's debut season.

Detroit (0-6) could not rally as it did in closely contested setbacks against San Francisco, Baltimore and Minnesota, failing to score until Austin Seibert made a 35-yard field goal midway through the fourth quarter. The Lions are the NFL's only winless team under first-year coach Dan Campbell. They have lost 10 straight going back to last season for the league's longest active losing streak.

Burrow finished 19 of 29 for 271 yards, including a 24-yard touchdown pass to rookie running back Chris Evans on the game's opening drive. He threw a short pass to Joe Mixon on fourth down that the running back turned into a 40-yard score in the second half to give Cincinnati a 17-0 lead. The second-year quarterback tossed a 2-yard touchdown to C.J. Uzomah early in the fourth, putting the Bengals ahead 27-0.

Steelers take OT win over Seahawks

Chris Boswell hit a 36-yard field goal with 2:50 left in overtime to give Pittsburgh a win over Seattle.

Boswell's third field goal of the game came three plays after Steelers outside linebacker T.J. Watt forced Seattle quarterback Geno Smith to fumble deep in Seahawks territory. Pittsburgh inside linebacker Devin Bush scooped it up to give the Steelers possession. Two snaps to center the ball in the middle of the field set up Boswell to win it.

Pittsburgh (3-3) won its second straight thanks in large part to Watt, who collected two of his team's five sacks and helped the defense right itself after a third-quarter soon let the Seahawks rally from a 14-point halftime deficit.

Ben Roethlisberger threw for 229 yards and a touchdown and rookie running back Najee Harris added 83 yards rushing and caught his second scoring toss of the season. Eric Ebron scored the third rushing touchdown of his career.

Vikings drop Panthers

Kirk Cousins completed a 27-yard touchdown pass to K.J. Osborn on the first possession of overtime to cap off Minnesota's 34-28 victory over Carolina.

Cousins threw for 373 yards and three touchdowns against the league's top-ranked pass defense, Dalvin Cook ran for 140 yards and a score and the Vikings finally solved their second-half offensive woes. Adam Thielen had a number of big catches, finishing with 11 receptions for 126 yards and a touchdown.

The Vikings (3-3) had not scored a second-half touchdown in their previous four games, but Cook broke the streak with a 16-yard touchdown run to give the Vikings the lead and Cousins added a 5-yard touchdown pass to Thielen.