Aug 24: Can drugs replace a healthy lifestyle? And more...

Blue and fin whales breed, sun turns into white dwarf, ecosystem interdependence, and losing tails

Image | Ozempic boxes

Caption: Early evidence suggests that GLP-1 agonist drugs like Ozempic may also work to treat kidney disease, addiction related disorders, metabolic liver disease, peripheral vascular disease, Parkinson's and Alzheimer's. (George Frey/Reuters)

On this week's episode of the Best of Quirks & Quarks with Bob McDonald:
Blue whales are genetically healthy but are breeding with fin whales, study suggests

Media Audio | Quirks and Quarks : Blue whales are genetically healthy but are breeding with fin whales, study suggests

Open Full Embed in New Tab (external link)Loading external pages may require significantly more data usage.
Researchers have sequenced the genome of a blue whale that washed up in Newfoundland in 2014, and used it to do a comparative study of North Atlantic blue whales. A team led by Mark Engstrom, curator emeritus at the Royal Ontario Museum, found that despite their small population, the whales are genetically diverse and connected across the North Atlantic — but also, surprisingly, the average blue whales from this group are, genetically, about 3.5 per cent fin whale. The work was published in the journal Conservation Genetics(external link).

Image | NL Whale Carcasses ROM curator May 10 2014

Caption: In 2014, Mark Engstrom, curator emeritus at the Royal Ontario Museum, and his team cut up the carcass of a blue whale in Winter House Brook, N.L. They have now sequenced its genome, and presented the results in a new study. (Paul Daly/Canadian Press)

What will become of our solar system as our sun evolves into a white dwarf star?

Media Audio | Quirks and Quarks : What will become of our solar system as our sun evolves into a white dwarf star?

Open Full Embed in New Tab (external link)Loading external pages may require significantly more data usage.
Over many billions of years, our sun, and stars of similar size, will first swell into a red giant star, and then contract into a small, dense white dwarf star. A new study using the James Webb Space Telescope has surveyed nearby white dwarf star systems to understand the fate of their planets, and astronomer Susan Mullally(external link) says this can help predict our planet's fate as well. Their research(external link) will appear in the Astrophysical Journal Letters.

Image | White Dwarf

Caption: The James Webb Space Telescope took this image of the Southern Ring Nebula with a white dwarf visible in centre. New research examines the fate of the planets in the dwarf's system. (NASA/ESA/CSA/STScI)

There was an old elephant who swallowed an ant…

Media Audio | Quirks and Quarks : There was an old elephant who swallowed an ant…

Open Full Embed in New Tab (external link)Loading external pages may require significantly more data usage.
The complex interdependence of plants and animals in an ecosystem are often hard to fathom until they go wrong. This is illustrated by a new study in Kenya, which showed how an invasive ant led to elephants knocking down trees, affecting how lions hunt zebras, which turned out to be bad news for buffalo. Adam Ford (external link)from the University of British Columbia, Okanagan is part of the team on this study(external link) published in Science.

Image | female lion yawning

Caption: A female lion in Kenya. (Submitted by Adam Ford)

The tiny genetic fluke that led humans — and other great apes — to lose our tails

Media Audio | Quirks and Quarks : The tiny genetic fluke that led humans — and other apes — to lose our tails

Open Full Embed in New Tab (external link)Loading external pages may require significantly more data usage.
In our evolutionary history, a fragment of genetic material accidentally found itself in in a gene long known to be important for the development of our entire back end. The result of this mutation, according to a study(external link) in the journal Nature, was our ape ancestors lost their tail — and we remain tail-less to this day. Itai Yanai(external link), a cancer biologist from New York University Grossman Medical School, identified the mutation, and found when they duplicated it in mice, they also lost their tails.

Image | 1242179683

Caption: These baboons in a Berlin zoo held on to their tails. Scientists have discovered a simple genetic mutation that led to humans, chimpanzees, gorillas, orangutans and gibbons to lose their tails approximately 25 million years ago. (Ina Fassbender/AFP/Getty Images)

Better living through pharmacology — Can drugs duplicate a healthy lifestyle?

Media Audio | Quirks and Quarks : Better living through pharmacology — Can drugs duplicate a healthy lifestyle?

Open Full Embed in New Tab (external link)Loading external pages may require significantly more data usage.
The key to good health used to be simple: eat less and exercise. But popular new weight loss drugs could soon be joined on the shelf with a new class of pharmaceuticals that duplicate the effects of a trip to the gym. We explore just how these new pharmaceuticals work, and just how much they can replace a healthy lifestyle.
First developed to treat type 2 diabetes, now widely popular as weight loss drugs, GLP-1 agonist drugs like Ozempic may have benefits beyond helping with obesity and cardiovascular disease. Dr. Daniel Drucker(external link), a senior research scientist at Lunenfeld-Tanenbaum Research Institute and the University of Toronto, said early evidence suggests they may also work to treat kidney disease, addiction related disorders, metabolic liver disease, peripheral vascular disease, Parkinson's and Alzheimer's.
To counter our modern sedentary lifestyles, scientists are also looking for the equivalent of an exercise pill. Ronald Evans(external link), a professor at the Salk Institute, has been working on drugs that control genetic "master switches" that can turn on the same network of genes — and confer many of the same benefits — as a brisk walk or a jog would do.

Image | HEALTH-OBESITY/OZEMPIC

Caption: Ozempic is part of a larger class of drugs developed to treat type 2 diabetes, obesity and cardiovascular disease. But researchers are investigating whether the drugs have much wider benefit for other illnesses. (Lee Smith/Reuters)