Digging a New Antibiotic out of the Dirt

Image | Hands in Soil

Caption: Sometimes science involves getting your hands dirty. (M Tullottes)

Audio | Quirks and Quarks : Pulling A New Antibiotic Out Of The Dirt - 2015/01/10 - Pt. 3

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Antibiotics are one of the great success stories of modern medicine, but few new ones have been developed since the 1960's, and many pathogens are evolving resistance to those. Now, a team led by Dr. Kim Lewis(external link), a professor of biology from Northeastern University in Boston, has discovered a new and potentially very effective antibiotic, using a technique that may open the door to even more new drugs. Many antibiotics come from soil bacteria that produce active molecules to fight each other. But easily cultured soil bacteria had been mined out in the first decades of discovery. So Dr. Lewis and his group developed a technology for growing bacteria that had previously been un-culturable, and thus opened up huge diversity of new species of bacteria that can be studied for their chemical creativity.
Related Links
- Paper(external link) in Nature
- News & Views(external link) in Nature
- Northeastern University release(external link)
- Nature news story(external link)
- CBC News story
- Smithsonian Magazine story(external link)