Canada's Jordan Romano made his major league debut with the Toronto Blue Jays on Wednesday night, pitching a perfect inning against the Baltimore Orioles.

Romano, from Markham, Ont., came into the game in the seventh inning and struck out two batters.

He got the first batter he faced, Pedro Severino, looking on a slider, then followed that with a swinging strikeout on Rio Ruiz on three straight pitches. He got Hanser Alberto to ground out to end the inning through a steady rainfall at Camden Yards.

The 26-year-old right-hander was all smiles in the dugout after his debut frame as he was met with congratulatory high-fives and hugs from his teammates, who nearly blew a big lead but held on to win.

Rowdy Tellez hit a grand slam to cap a six-run fifth inning, Vladimir Guerrero Jr. had three hits and the Blue Jays beat the Orioles 8-6 to end a five-game losing streak.

Lourdes Gurriel Jr. had two RBIs for the Blue Jays, who matched their run total from the previous five games combined.

"A lot of times one guy has a good at-bat and the next two guys don't have good at-bats," manager Charlie Montoyo said. "But today, one by one, they had good at-bats. So that helped."

Toronto sent nine batters to the plate in the fifth, scoring on an infield single and a wild pitch before Tellez sent a 2-2 pitch from Miguel Castro over the right-field scoreboard . It was the second grand slam of the season for the rookie, who had gone hitless in his previous 11 at-bats.

Trey Mancini homered for the Orioles, who won the series opener and were trying to put together back-to-back victories for the first time since May 4-6.

Baltimore used a four-run eighth to cut into an 8-2 deficit but could not complete the comeback.

Pitching in his 400th career game, Edwin Jackson (1-4) allowed two runs in five innings of relief for Toronto. The 35-year-old was initially listed as the starter, but manager Charlie Montoyo switched to opener Derek Law so the struggling Jackson could avoid facing the top of the Baltimore batting order at the outset.

Law pitched a scoreless first inning before giving way to Jackson, who came in with an 11.90 ERA over five starts.

Backed by a rare offensive outburst from the Blue Jays, Jackson earned his first win since Sept. 20.

"It's always good when you're having fun and you're scoring a lot of runs," the right-hander said. "It was good for that to happen to the team, just that little reassurance of the things they're capable of doing."

Daniel Hudson quelled Baltimore's uprising in the eighth and earned his first save by getting three straight outs after the Orioles put runners on second and third.

Romano was called up from triple-A Buffalo earlier Wednesday when closer Ken Giles was placed on the 10-day injured list with right elbow inflammation.

Romano was 1-2 with a 6.10 earned-run average over 31 innings pitched for Buffalo before receiving his promotion to the big leagues. He had a shaky start to the season with the Bisons put had turned a corner over the last three weeks, allowing zero runs over his last eight appearances out of the bullpen.

Romano is the 28th Canadian to play for Blue Jays. He was drafted by Toronto out of Oral Roberts University in the 10th round in 2014.

He was left unprotected by the Blue Jays at the most recent Rule 5 draft and was picked up by the Chicago White Sox in before being traded to the Texas Rangers that same day. Romano did not make the Rangers roster out of spring training, allowing him to go back to the Blue Jays.

Romano is the 12th Canadian to appear in a major league game this year.